2-叠氮基-1-甲基苯并咪唑合成路线 （共 6 条）
反应条件
sodium azide; 15-crown-5; tributyltin chloride; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran 48 h; Heating;
参考文献
Ohta, Shunsaku; Tsuno, Naoki; Nakamura, Seikou; Taguchi, Norio; Yamashita, Masayuki; Kawasaki, Ikuo; Fujieda, Mieko
Heterocycles, 2000 , vol. 53, # 9 p. 1939 - 1955
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: With 4-toluenesulfonyl azide in tetrahydrofuran 0.5 h;
参考文献
Ohta, Shunsaku; Tsuno, Naoki; Nakamura, Seikou; Taguchi, Norio; Yamashita, Masayuki; Kawasaki, Ikuo; Fujieda, Mieko
Heterocycles, 2000 , vol. 53, # 9 p. 1939 - 1955
反应条件
hydrogenchloride; sodium nitrite in ethanol; water T=0°C;
参考文献
Zornik, Denise; Meudtner, Robert M.; Ela Malah, Tamer; Thiele, Christina M.; Hecht, Stefan
Chemistry - A European Journal, 2011 , vol. 17, # 5 p. 1473 - 1484
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 0 °C 1.2: 0.25 h / 0 °C 2.1: hydrazine hydrate / 160 °C 3.1: hydrogenchloride; sodium nitrite / ethanol; water / 0 °C View Scheme
参考文献
Zornik, Denise; Meudtner, Robert M.; Ela Malah, Tamer; Thiele, Christina M.; Hecht, Stefan
Chemistry - A European Journal, 2011 , vol. 17, # 5 p. 1473 - 1484
反应条件
1: hydrazine hydrate / 160 °C 2: hydrogenchloride; sodium nitrite / ethanol; water / 0 °C View Scheme
参考文献
Zornik, Denise; Meudtner, Robert M.; Ela Malah, Tamer; Thiele, Christina M.; Hecht, Stefan
Chemistry - A European Journal, 2011 , vol. 17, # 5 p. 1473 - 1484
反应条件
hydrogen; palladium on activated charcoal
参考文献
Ohta, Shunsaku; Tsuno, Naoki; Nakamura, Seikou; Taguchi, Norio; Yamashita, Masayuki; Kawasaki, Ikuo; Fujieda, Mieko
Heterocycles, 2000 , vol. 53, # 9 p. 1939 - 1955
