1: 4-bromo-2,6-di-tert-butylphenol With sodium hydride in tetrahydrofuran T=20°C; 1 h; 2: dimethyl sulfate in tetrahydrofuran 17 h; Heating;

1: 4-bromo-2,6-di-tert-butylphenol With sodium hydride in dimethyl sulfoxide; oil T=0°C; Inert atmosphere; 2: methyl iodide in dimethyl sulfoxide; oil T=0 - 20°C; Inert atmosphere;

N-bromosuccinmide in acetonitrile 48 h;

lithium in tetrahydrofuran; tert-butyl alcohol T=70°C; 8 h;

1: tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate 2: N-bromosuccinmide 3: [1,3-bis(diphenylphosphino) propane] dichloronickel(II); magnesium View Scheme

1: 1-bromo-3,5-di-tert-butyl-4-methoxybenzene With iodine; magnesium in tetrahydrofuran T=5 - 53°C; 2 h; 2: dimethyl hydrogen phosphite in tetrahydrofuran T=5°C; 1 h; 3: With hydrogenchloride; water in tetrahydrofuran; toluene T=20°C; 0.5 h;

1: With magnesium in tetrahydrofuran T=40°C; 2: With phosphonic acid diethyl ester in tetrahydrofuran T=25°C;