(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 10 h; Inert atmosphere; optical yield given as percent ee;
参考文献
Organic Letters, , vol. 13, # 15 p. 3794 - 3797
反应条件
(R)-(+)-N-methylbenzoguanidine; trimethylacetic anhydride in diethyl ether T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Nakata, Kenya; Shiina, Isamu
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 7092 - 7096
反应条件
hydrogen; lipase B from Candida antarctica in toluene T=70°C; P=750.075 Torr; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
European Journal of Organic Chemistry, , vol. 2014, # 14 p. 2917 - 2923
反应条件
1-[(Ph2C(OH)]-2-[(S)-4-(t-Bu)oxazolin-2-yl]ferrocene in toluene T=0°C; Addition; 15 h; Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 14 p. 1295 - 1296
反应条件
sodium hydroxide; hydrogen; palladium on activated charcoal in ethanol T=20°C; Hydrogenation; Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 16 p. 2397 - 2402
反应条件
lithium hydroxide in tetrahydrofuran; water 3 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 67, # 6 p. 1781 - 1785
反应条件
ethanol; boron trifluoride diethyl etherate T=50°C; 0.5 h; Product distribution / selectivity;
参考文献
WO2005/70911 A1, ;
Page/Page column 95 ;
反应条件
1: acetyl chloride With pyridine; C44H45O4P in toluene T=20°C; 0.0833333 h; Inert atmosphereResolution of racemate; 2: sec-phenethyl alcohol in toluene T=0°C; 15 h; Resolution of racemateInert atmosphere;
参考文献
Organic Letters, , vol. 14, # 13 p. 3486 - 3489
反应条件
(R)-4-(diphenylhydroxymethyl)-1,3-thiazolidine 1.) toluene, from -20 deg C to RT, 2.) toluene, RT, 16 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 8, # 12 p. 2033 - 2043
反应条件
Candida antarctica lipase B in various solvent(s) T=28°C; 46 h; Further byproducts given;
参考文献
Gonzalez-Sabin, Javier; Gotor, Vicente; Rebolledo, Francisca
Tetrahedron Asymmetry, 2004 , vol. 15, # 3 p. 481 - 488
