(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
[(C4Ph4COHOCC4Ph4)(μ-H)][(CO)4Ru2]; Novozym(R) 435; 2,4-dimethylpentan-3-one in toluene T=70°C; P=142.511 Torr; 40 h;
参考文献
Verzijl, Gerard K.M.; De Vries, Johannes G.; Broxterman, Quirinus B.
Tetrahedron Asymmetry, 2005 , vol. 16, # 9 p. 1603 - 1610
反应条件
potassium tert-butylate; η5-Ph5CpRu(CO)2Cl in tetrahydrofuran; toluene T=20°C;
参考文献
Chemistry - A European Journal, , vol. 13, # 21 p. 6063 - 6072
反应条件
Novozym 435(R); 1-n-butyl-3-methylimidazolium hexafluorophosphate T=35°C; 24 h;
参考文献
Angewandte Chemie - International Edition, , vol. 46, # 43 p. 8178 - 8181
反应条件
Novozym 435(R); 1-n-butyl-3-methylimidazolium tetrafluoroborate T=35°C; 24 h;
参考文献
Angewandte Chemie - International Edition, , vol. 46, # 43 p. 8178 - 8181
反应条件
methanol; sodium hydroxide T=20°C; 1 h; Inert atmosphere;
参考文献
Issenhuth, Jean-Thomas; Dagorne, Samuel; Bellemin-Laponnaz, Stephane
Comptes Rendus Chimie, 2010 , vol. 13, # 3 p. 353 - 357
反应条件
1: sec-phenethyl alcohol With iPr2NCHEt2; (-)-Tetramisole in tetrahydrofuran T=-78°C; 0.5 h; Molecular sieveInert atmosphereResolution of racemate; 2: triphenyl-silyl chloride in tetrahydrofuran T=-78°C; Inert atmosphereResolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Organic Letters, , vol. 13, # 15 p. 3794 - 3797
反应条件
lipase B; hydrogen T=50°C; P=4200.42 Torr; 5 h; Enzymatic reaction;
参考文献
Research on Chemical Intermediates, , vol. 36, # 3 p. 245 - 252
反应条件
Fu's catalyst; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; triethylamine in 1,1-dimethylpropan-1-ol T=0°C; Resolution of racemate; Time;
参考文献
Lee, Sarah Yunmi; Murphy, Jaclyn M.; Ukai, Atsushi; Fu, Gregory C.
Journal of the American Chemical Society, 2012 , vol. 134, # 36 p. 15149 - 15153
反应条件
toluene-4-sulfonic acid in methanol 3 h;
参考文献
Noe, Christian R.
Chemische Berichte, 1982 , vol. 115, # 4 p. 1591 - 1606
反应条件
in diethyl ether Yield given. Yields of byproduct given;
参考文献
Angewandte Chemie, , vol. 103, # 1 p. 100 - 101
