(R)-(+)-1-苯基乙醇合成路线 (共 353 条)
反应条件
Candida antarctica lipase B in diethyl ether T=20°C; 144 h; Enzymatic reaction; optical yield given as percent ee;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 10 p. 1191 - 1196
反应条件
CAL B T=35°C; P=100 Torr; 168 h; Ionic liquidResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 36 p. 6938 - 6943
反应条件
CAL B T=35°C; P=100 Torr; 168 h; Ionic liquidResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 36 p. 6938 - 6943
反应条件
2-acetyloxy-1-propene; lipase YS in di-isopropyl ether T=30°C; 19 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 1253 - 1256
反应条件
potassium hydroxide; ethanol; 3-chloro-benzenecarboperoxoic acid 1.) 1,2-dichloroethane, , room temperature, 72 h, 2.) H2O, reflux, 3 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 103, # 11 p. 3088 - 3093
反应条件
in dichloromethane T=0°C; hydroxylation by a chiral iron porphyrin, deuterium isotope effect;
参考文献
Journal of the American Chemical Society, , vol. 111, # 22 p. 8537 - 8538
反应条件
in dichloromethane T=0°C; hydroxylation by a chiral iron porphyrin, deuterium isotope effect;
参考文献
Journal of the American Chemical Society, , vol. 111, # 22 p. 8537 - 8538
反应条件
Rhizopus nigricans (sterile potato dextrose medium) in tetrahydrofuran 16 h; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ziffer, Herman; Kawai, Ken-ichi; Kasai, Masaji; Imuta, Mitsuru; Froussios, Cleanthis
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3017 - 3021
反应条件
n-butyllithium; (2S,2'S)-2-hydroxymethyl-1-lt;(1-methylpyrrolidine-2-yl)methylgt;pyrrolidine investigation of the asymmetric addition of alkyllithium to an aldehyde in presence (2S,2S')-2-hydroxymethyl-1-<(1-methylpyrrolidine-2-yl)methyl>pyrrolidine; Product distributionMechanism;
参考文献
Tetrahedron, , vol. 37, # 23 p. 4111 - 4119
反应条件
sodium hydroxide T=25°C; 4 h;
参考文献
Journal of Organic Chemistry, , vol. 53, # 23 p. 5531 - 5534