(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
lithium aluminium tetrahydride in ethylene glycol dimethyl ether 12 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 53, # 26 p. 6130 - 6133
参考文献
Noe, Christian R.; Knollmueller, Max; Wagner, Ernst; Voellenkle, Horst
Chemische Berichte, 1985 , vol. 118, # 5 p. 1733 - 1745
反应条件
potassium hydroxide Heating;
参考文献
Reyes; Juaristi
Synthetic Communications, 1995 , vol. 25, # 7 p. 1053 - 1058
反应条件
polymer-bound TADDOL in toluene T=-75 - 0°C; 16 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Helvetica Chimica Acta, , vol. 79, # 6 p. 1710 - 1740
反应条件
Aspergillus niger biotransformation by diverse microorganisms, conversion percent, enantiomeric excess; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 63, # 22 p. 7598 - 7599
反应条件
1: trimethylaluminum With titanium(IV) isopropylate; (S)-2-hydroxy-3-phenylpropionic acid in tetrahydrofuran; toluene T=22°C; 2.5 h; 2: benzaldehyde in tetrahydrofuran; toluene T=22°C; 2.5 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 16, # 4 p. 851 - 855
反应条件
1: 90 percent Spectr. / diborane / toluene / -78 °C 2: Raney Ni View Scheme
参考文献
Journal of Organic Chemistry, , vol. 47, # 7 p. 1196 - 1200
反应条件
1: 1.) n-BuLi / 1.) THF, 0 deg C, 15 min, 2.) room temp., overnight 2: 90 percent Spectr. / diborane / toluene / -78 °C 3: Raney Ni View Scheme
参考文献
Journal of Organic Chemistry, , vol. 47, # 7 p. 1196 - 1200
反应条件
1: With (4R,5R)-DIOP; [{RhCl(cod)}2] in tetrahydrofuran T=20°C; 4 h; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran; water optical yield given as percent ee;
参考文献
Marques, Carolina S.; Burke, Anthony J.
Synthetic Communications, 2008 , vol. 38, # 23 p. 4207 - 4214
反应条件
1: With tetracarbonylbis(μ-chloro)dirhodium(I); (R)-(+)-bornylamine in tetrahydrofuran T=0 - 2°C; 2: With hydrogenchloride; water in methanol optical yield given as percent eeenantioselective reaction;
参考文献
Russian Journal of General Chemistry, , vol. 80, # 1 p. 35 - 46
