(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
Me3NO; C23H16FeO5; triethylamine T=40°C; 96 h; optical yield given as percent eeenantioselective reaction;
参考文献
Hopewell, Jonathan P.; Martins, Jose E. D.; Johnson, Tarn C.; Godfrey, Jamie; Wills, Martin
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 1 p. 134 - 145
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / diethyl ether 2: sodium carbonate / toluene / 72 h / 40 °C / Enzymatic reaction View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 23, # 11-12 p. 828 - 833
反应条件
lipase B from Candida antarctica in toluene T=70°C; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
European Journal of Organic Chemistry, , vol. 2014, # 14 p. 2917 - 2923
反应条件
ammonia in tert-butyl alcohol 120 h; Ambient temperatureCandida antarctica lipase SP435;
参考文献
Zoete, Marian C. de; Kock-van Dalen, Alida C.; Rantwijk, Fred van; Sheldon, Roger A.
Journal of the Chemical Society, Chemical Communications, 1993 , # 24 p. 1831 - 1832
反应条件
sodium tetrahydroborate; alpha-cyclodextrin in water 48 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 64, # 6 p. 1884 - 1888
反应条件
C33H34O4*C9H21ClO3Ti in tetrahydrofuran from -78 degC to room t.; Yield given. Yields of byproduct given;
参考文献
Helvetica Chimica Acta, , vol. 70, p. 954 - 974
反应条件
toluene-4-sulfonic acid in chloroform 1 h; Ambient temperature;
参考文献
Chemische Berichte, , vol. 118, # 8 p. 3299 - 3310
反应条件
1: 95 percent / pyridine, 4-(dimethylamino)pyridine / Ambient temperature 2: 1) KF, KHCO3, 2) 30percent H2O2 / 1) THF, MeOH, 2) THF, MeOH, 60 deg C, 15 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 25 p. 7076 - 7083
反应条件
CAL B T=35°C; 1 h; Ionic liquidResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 36 p. 6938 - 6943
反应条件
lipase from Burkholderia cepacia (free form) -conjugated magnetic nanobead T=30°C; pH=7.4; 24 h; aq. phosphate buffer; optical yield given as percent ee;
参考文献
Tetrahedron Letters, , vol. 52, # 9 p. 1041 - 1043
