(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
1.1: sodium tetrahydroborate / methanol / 0.5 h / 20 °C 1.2: 0.17 h / 20 °C / Saturated solution 2.1: Escherichia coli BioH esterase immobilized on Macroporous adsorptive resin / 35 °C / Enzymatic reaction 3.1: immobilized CALB lipase / di-isopropyl ether / 8 h / 35 °C / Enzymatic reaction View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 9 p. 980 - 985
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C / |Inert atmosphere 2: lipase from candida antartica / aq. phosphate buffer / 24 h / 30 °C / pH 6.5 View Scheme
参考文献
Letters in Organic Chemistry, , vol. 9, # 9 p. 615 - 621
反应条件
hydrogenchloride; water in dichloromethane Inert atmosphere;
参考文献
Chemical Communications, , vol. 49, # 43 p. 4893 - 4895
反应条件
hydrogenchloride; water in dichloromethane Inert atmosphere;
参考文献
Chemical Communications, , vol. 49, # 43 p. 4893 - 4895
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate 1) THF, MeOH, 2) THF, MeOH, 60 deg C, 15 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 56, # 25 p. 7076 - 7083
反应条件
alkaline H2O2; lithium triethylborohydride 1.) THF, RT, overnight; Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 50, # 9 p. 1384 - 1394
反应条件
nickel Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 47, # 7 p. 1196 - 1200
反应条件
2BH3*NH2CH2CH2NH2 in solid enantioselective reduction of var. ketones in optically active host compounds with a BH3-ethylenediamine complex in the solid state; Product distribution;
参考文献
Toda, Fumio; Mori, Koji
Journal of the Chemical Society, Chemical Communications, 1989 , # 17 p. 1245 - 1246
反应条件
Coprinus peroxidase (CiP); 2-methoxy-phenol in water T=20°C; 4 h; phosphate buffer pH 7.0; enzyme-catalyzed kinetic resolution of chiral hydroperoxides in the presence and absence of guaiacol; selectivity; enantiomeric excess; CiP-catalyzed disproportionation; resolution via CiP-catalyzed sulfoxidation; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 64, # 13 p. 4834 - 4839
反应条件
N,N-bis-2-(hydroxyethyl)-2-amino ethane sulfonic acid; esterase from Streptomyces diastatochromogenes in water T=25°C; pH=7.20; Enzyme kinetics;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 4 p. 545 - 556
