(R)-(+)-1-苯基乙醇合成路线 (共 353 条)
反应条件
HEPES buffer; Catharanthus roseus GTF-I glucosyltransferase T=35°C; pH=7.0; 36 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 15, # 15 p. 2319 - 2321
反应条件
Multistep reaction. Title compound not separated from byproducts.;
参考文献
Angewandte Chemie - International Edition, , vol. 46, # 39 p. 7491 - 7494
反应条件
Bacillus sp. Cohn 1872 cells T=28°C; pH=7; aq. phosphate bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of the Brazilian Chemical Society, , vol. 21, # 8 p. 1484 - 1489
反应条件
lipase from Candida rugosa-conjugated magnetic nanobead T=30°C; pH=7.4; 24 h; aq. phosphate buffer; optical yield given as percent ee;
参考文献
Tetrahedron Letters, , vol. 52, # 9 p. 1041 - 1043
反应条件
1: sodium tetrahydroborate 2: steapsin lipase / hexane / 24 h / 55 °C / Enzymatic reaction View Scheme
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 77, p. 15 - 23
反应条件
1: triethylamine / dichloromethane / 0 °C 2: Lipase Amano AK / 30 h / 20 °C / pH 7 / aq. phosphate buffer; Enzymatic reaction View Scheme
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 72, # 3-4 p. 270 - 275
反应条件
1: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 20 °C / |Inert atmosphere 2: lipase from candida antartica / aq. phosphate buffer / 24 h / 30 °C / pH 6.5 View Scheme
参考文献
Letters in Organic Chemistry, , vol. 9, # 9 p. 615 - 621
反应条件
sodium hydroxide 6 h; Ambient temperature; Yield given;
参考文献
Tetrahedron: Asymmetry, , vol. 4, # 5 p. 839 - 844
反应条件
sodium hydroxide; lithium aluminium tetrahydride 1.) Et2O, THF, 16h 2.) 4h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 46, # 13/14 p. 4994 - 5026
参考文献
Tetrahedron Letters, , vol. 25, # 36 p. 3979 - 3982