(R)-(+)-1-苯基乙醇 合成路线 （共 353 条）
反应条件
hydrogenchloride; water in methanol T=20°C; 2 h; Inert atmosphere; optical yield given as percent ee;
参考文献
Motoyama, Yukihiro; Abe, Motonori; Kamo, Kazuyuki; Kosako, Yusuke; Nagashima, Hideo
反应条件
1: With formic acid T=100°C; 0.5 h; Inert atmosphereSealed tube; 2: With Rh-(S,S)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine; water; sodium hydroxide T=20 - 40°C; pH=7; 3 h; enantioselective reaction;
参考文献
Li, Jia; Wang, Chao; Xue, Dong; Wei, Yawen; Xiao, Jianliang
反应条件
tetraethylammonium iodide; CND in water; acetonitrile T=25°C; Electrolysis; SolventReagent/catalyst; enantioselective reaction;
参考文献
Electrochimica Acta, , vol. 107, p. 320 - 326
反应条件
hydrogen; lipase B from Candida antarctica in toluene T=70°C; P=750.075 Torr; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
European Journal of Organic Chemistry, , vol. 2014, # 14 p. 2917 - 2923
反应条件
sodium hydrogencarbonate; sodium bromide; chiral 4,1'-dinaphthyl-3,2'-cyclo[C(Me)2-N(oxyl)-C(Me)2] in dichloromethane; water T=-15°C; Dehydrogenation; resolution of racemate; 1.5 h; Electrolysis; Product distribution; Further Variations:Reaction partnersTemperatureselectricity;
参考文献
Kuroboshi; Yoshihisa; Cortona; Kawakami; Gao; Tanaka
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol 16 h;
参考文献
Guo, Xun-Xiang; Xie, Jian-Hua; Hou, Guo-Hua; Shi, Wen-Jian; Wang, Li-Xin; Zhou, Qi-Lin
反应条件
(S)-(-)-2-lt;2',2'-dimethyl-1'-(2''-pyridyl)propoxygt;-1,1-di-(α-naphthyl)ethanol in hexane 4 h; Ambient temperatureother aldehydes, other dialkylzinc, var. chiral alcohols as ligands, var. reaction time; Product distributionMechanism;
参考文献
Tetrahedron Asymmetry, , vol. 5, # 3 p. 411 - 424
反应条件
chiral 2-(3',5'-di-t-butylPh)-2-phosphabicyclo[3.3.0]octane in toluene T=-40°C; 4.5 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 125, # 14 p. 4166 - 4173
344580-04-7 2,2,2-三氟乙基4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-十七氟十一烷酸酯
→
反应条件
反应条件
1: With lipase B from Candida antarctica in acetonitrile T=20°C; 19 h; 2: With lithium hydroxide in tetrahydrofuran; water 3 h; Heating;
参考文献
Angewandte Chemie - International Edition, , vol. 40, # 13 p. 2492 - 2494
反应条件
Novozym 435; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η5-C4CNH(i-Pr))]Ru(CO)2Cl in toluene T=25°C; 96 h;
参考文献
Choi, Jun Ho; Choi, Yoon Kyung; Kim, Yu Hwan; Park, Eun Sil; Kim, Eun Jung; Kim, Mahn-Joo; Park, Jaiwook
