(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
(S,S)-2,3-O-isopropylidene-1,1,4,4-tetraphenylthreitol in hexane T=20°C; 72 h;
参考文献
Vinogradov; Gorshkova; Chel'tsova; Kurilov; Ferapontov; Shishkin; Heise
Russian Chemical Bulletin, 2003 , vol. 52, # 8 p. 1841 - 1846
反应条件
1: With hydrogen; [Ru{(S)-MeO-BIPHEP}Br2] in methanol T=25°C; Hydrogenation; P=37503.8 Torr; 2: With nickel desulfurization; Further stages. Title compound not separated from byproducts.;
参考文献
European Journal of Organic Chemistry, , # 8 p. 1535 - 1537
反应条件
titanium(IV) isopropylate; (R,S)-2-OH-3,5-Cl2-C6H2-SO2-NH-CH(CH2Ph)-CH(Ph)OH in tetrahydrofuran T=0°C; 12 h;
参考文献
You; Hsieh; Gau
Chemical Communications, 2001 , # 17 p. 1546 - 1547
反应条件
C48H48N2O4Ru2 in benzene T=30°C; 20 h; IrradiationDarkness; optical yield given as percent ee;
参考文献
Do, Youngshil; Hwang, In-Chul; Kim, Mahn-Joo; Park, Jaiwook
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5740 - 5742
反应条件
hydrogen; lipase B from Candida antarctica in toluene T=70°C; P=750.075 Torr; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
European Journal of Organic Chemistry, , vol. 2014, # 14 p. 2917 - 2923
反应条件
potassium hydroxide; [Ir(μ-Cl)(1,5-cyclooctadiene)]2; polymer containing chiral cyclohexanediimine; styrene and divinylbenzene Ambient temperatureother polymers as ligands; Product distribution;
参考文献
Tetrahedron Asymmetry, , vol. 9, # 6 p. 897 - 900
反应条件
1: 87 percent / trichlorosilane; allylpalladium chloride dimer / (SA,RC,RC)-BINOL=P-N-(1-ethylphenyl)2 / 16 h / 20 °C 2: KF; KHCO3; aq. H2O2 / methanol; tetrahydrofuran / 16 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 17 p. 4558 - 4559
反应条件
diphosphorous tetraiodide; tetraethylammonium bromide; water in dichloromethane T=20°C; 6 h; regioselective reaction;
参考文献
Telvekar, Vikas N.; Rane, Rajesh A.
Synthetic Communications, 2010 , vol. 40, # 14 p. 2108 - 2112
反应条件
triethylamine in tert-butyl methyl ether T=50°C; 216 h; Inert atmosphereEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Quijada, F. Javier; Gotor, Vicente; Rebolledo, Francisca
Organic Letters, 2010 , vol. 12, # 16 p. 3602 - 3605
反应条件
water; potassium hydroxide in methanol T=20°C; 24 h;
参考文献
Ha, Min Woo; Hong, Suckchang; Park, Cheonhyoung; Park, Yohan; Lee, Jihye; Kim, Mi-Hyun; Lee, Jihoon; Park, Hyeung-Geun
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 24 p. 4030 - 4039
