(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
sodium hydroxide; dihydrogen peroxide; benzo[1,3,2]dioxaborole; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; (R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl in ethylene glycol dimethyl ether T=-78°C; 2 h; others temperatures, times, and solvents; various catalyts; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 111, # 9 p. 3426 - 3428
反应条件
titanium(IV) isopropylate; (S)-2,2'-dihydroxy-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl in tetrahydrofuran; toluene T=0°C; 5 h; asymmetric alkylation of various aromatic aldehydes, other asymmetric and alkylating agents; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 119, # 17 p. 4080 - 4081
反应条件
1: With hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; (R)-1,1'-bis(diphenylphosphino)-2,2'-binapthyl in 1,2-dichloro-ethane T=-20°C; P=6840 Torr; 168 h; 2: With dihydrogen peroxide; sodium acetate T=20°C; 2 h;
参考文献
Journal of Organometallic Chemistry, , vol. 642, # 1-2 p. 145 - 147
反应条件
4-bromooctafluorobutanetriethoxysilane; (S,S,S,S)-N,N'-di(α-phenylethyl)cyclohexane-1,2-diamine; diethylzinc in toluene T=20°C; 18 h; Title compound not separated from byproducts.;
参考文献
Mastranzo, Virginia M.; Quintero, Leticia; De Parrodi, Cecilia Anaya; Juaristi, Eusebio; Walsh, Patrick J.
Tetrahedron, 2004 , vol. 60, # 8 p. 1781 - 1789
反应条件
hydrogen; lipase B from Candida antarctica in toluene T=70°C; P=750.075 Torr; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
Xia, Bo; Cheng, Guilin; Lin, Xianfu; Wu, Qi
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2917 - 2923
反应条件
potassium fluoride; water; dihydrogen peroxide in N,N-dimethyl-formamide T=60°C; Oxidation; 1 h; Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 24 p. 2517 - 2518
反应条件
1: With pinacol borane; 4 A molecular sieve; chiral TADDOL-based reagent; [Rh(μ-Cl)(2,5-norbornadiene)]2 in ethylene glycol dimethyl ether T=0 - 20°C; 2: With sodium hydroxide; dihydrogen peroxide in methanol; ethylene glycol dimethyl ether; water T=0 - 20°C;
参考文献
Organic Letters, , vol. 8, # 14 p. 3097 - 3100
反应条件
water; sodium hydroxide in tetrahydrofuran; methanol T=20°C; 6 h; Inert atmosphere;
参考文献
Journal of the American Chemical Society, , vol. 132, p. 1264 - 1266
反应条件
dihydrogen peroxide 5 h; chloroperoxidase from Caldaromyces fumago, citrate buffer pH=5.0;
参考文献
Zaks; Dodds
Journal of the American Chemical Society, 1995 , vol. 117, # 42 p. 10419 - 10424
反应条件
Novozym 435(R); 1-n-butyl-3-methylimidazolium tetrafluoroborate T=35°C; P=100 Torr; 96 h;
参考文献
Angewandte Chemie - International Edition, , vol. 46, # 43 p. 8178 - 8181
