(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
SPB; water in tetrahydrofuran T=22°C;
参考文献
Angewandte Chemie, International Edition, , vol. 48, # 33 p. 6062 - 6064
Angewandte Chemie, , vol. 121, # 33 p. 6178 - 6180
反应条件
Candida antarctica polyacrylamide-immobilized lipase B, Novozyme SP-435 in tert-butyl methyl ether T=28°C; 144 h; Inert atmosphereMolecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Organic Letters, , vol. 12, # 16 p. 3602 - 3605
反应条件
lipase B; 10 palladium on activated charcoal; hydrogen in ethyl acetate T=50°C; P=4200.42 Torr; 5 h; Enzymatic reaction;
参考文献
Research on Chemical Intermediates, , vol. 36, # 3 p. 245 - 252
反应条件
5-chloro-4,9-(chlorobenzene-2,3-diyl)-2,4-dihydroxy-3a,4,9,9a-tetrahydro-1H-benzo[f]isoindole-1,3(2H)-dione; oxygen; anhydrous cobalt diacetate in acetonitrile T=60°C; P=760.051 Torr; enantioselective reaction;
参考文献
Shen, Juan; Tan, Choon-Hong
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 22 p. 4096 - 4098
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 3 h; Ambient temperature;
参考文献
Mangold, James B.; Abdel-Monem, Mahmoud M.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 1 p. 66 - 71
反应条件
n-butyllithium; (2S,2'S)-2-hydroxymethyl-1-lt;(1-methylpyrrolidine-2-yl)methylgt;pyrrolidine in toluene T=-110°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 37, # 23 p. 4111 - 4119
反应条件
BES buffer; Lipase from Burkholderia cepacia; calcium chloride in acetonitrile T=30°C; pH=7.2; 48 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 35 p. 12228 - 12229
反应条件
sodium formate; Triton X-100; [RuCl(η6-p-cymene)(N-tosyl-1,2-diphenylethylenediamine)] in water T=28°C; 6 h;
参考文献
Journal of Organic Chemistry, , vol. 70, # 23 p. 9424 - 9429
反应条件
Candida antarctica polyacrylamide-immobilized lipase B, Novozyme SP-435 in tert-butyl methyl ether T=28°C; 144 h; Inert atmosphereMolecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Quijada, F. Javier; Gotor, Vicente; Rebolledo, Francisca
Organic Letters, 2010 , vol. 12, # 16 p. 3602 - 3605
反应条件
Candida antarctica polyacrylamide-immobilized lipase B, Novozyme SP-435 in tert-butyl methyl ether T=28°C; 120 h; Inert atmosphereMolecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Quijada, F. Javier; Gotor, Vicente; Rebolledo, Francisca
Organic Letters, 2010 , vol. 12, # 16 p. 3602 - 3605
