(R)-(+)-1-苯基乙醇合成路线 (共 353 条)
反应条件
triethylamine in tert-butyl methyl ether T=50°C; 216 h; Inert atmosphereEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Quijada, F. Javier; Gotor, Vicente; Rebolledo, Francisca
Organic Letters, 2010 , vol. 12, # 16 p. 3602 - 3605
反应条件
Brassica rapa var. rapa peroxidase; 2-methoxy-phenol T=20°C; pH=6; 3.5 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 23, # 8 p. 594 - 601
反应条件
toluene-4-sulfonic acid; triethylamine in methanol 1 h; Ambient temperature;
参考文献
Knollmueller, Max; Noe, Christian R.; Steinbauer, Gerhard; Dungler, Karin
Synthesis, 1986 , # 6 p. 501 - 505
反应条件
hydrogen cation in water Yield given;
参考文献
Chemische Berichte, , vol. 117, # 4 p. 1330 - 1354
反应条件
4 A molecular sieve; Lipase from Burkholderia cepacia in 1,4-dioxane T=30°C; 48 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 35 p. 12228 - 12229
反应条件
polyoxyethylene (10) cetyl ether; n-octyl beta-D-glucopyranoside; subtilisin Carlsberg; (η5-C5Ph5)Ru(CO)2Cl; sodium carbonate in tetrahydrofuran T=20°C; 17 h; Title compound not separated from byproducts;
参考文献
Chemistry - A European Journal, , vol. 12, # 1 p. 225 - 232
反应条件
polyoxyethylene (10) cetyl ether; n-octyl beta-D-glucopyranoside; subtilisin Carlsberg; sodium carbonate in tetrahydrofuran T=20°C; 17 h; Title compound not separated from byproducts;
参考文献
Chemistry - A European Journal, , vol. 12, # 1 p. 225 - 232
反应条件
N-ethyl-N,N-diisopropylamine; CF3-PIP in chloroform T=0°C; 6 - 8.25 h; Resolution of racemate; Product distribution / selectivity;
参考文献
US2005/256150 A1, ;
Page/Page column 15; 16; 18; 19-20 ;
反应条件
Novozym 435(R); 1-n-butyl-3-methylimidazolium hexafluorophosphate T=35°C; P=100 Torr; 96 h; Title compound not separated from byproducts.;
参考文献
Angewandte Chemie - International Edition, , vol. 46, # 43 p. 8178 - 8181
反应条件
1: benzyl (+/-)-cis-(2-aminocyclopentyl)carbamate; 1-acetyloxyethylbenzene With Candida antarctica polyacrylamide-immobilized lipase B, Novozyme SP-435 in tert-butyl methyl ether T=28°C; 144 h; Inert atmosphereMolecular sieveEnzymatic reaction; 2: di-tert-butyl dicarbonate in tert-butyl methyl ether 0.0833333 h; optical yield given as percent eeenantioselective reaction;
参考文献
Quijada, F. Javier; Gotor, Vicente; Rebolledo, Francisca
Organic Letters, 2010 , vol. 12, # 16 p. 3602 - 3605