(R)-(+)-1-苯基乙醇合成路线 （共 353 条）
反应条件
1: allyl (+/-)-cis-(2-aminocyclopentyl)carbamate; 1-acetyloxyethylbenzene With Candida antarctica polyacrylamide-immobilized lipase B, Novozyme SP-435 in tert-butyl methyl ether T=28°C; 120 h; Inert atmosphereMolecular sieveEnzymatic reaction; 2: di-tert-butyl dicarbonate in tert-butyl methyl ether 0.0833333 h; optical yield given as percent eeenantioselective reaction;
参考文献
Quijada, F. Javier; Gotor, Vicente; Rebolledo, Francisca
Organic Letters, 2010 , vol. 12, # 16 p. 3602 - 3605
反应条件
1: dimethyl zinc; phenylacetylene With (-)-2-exo-morpholinoisobornane-10-thiol in hexane T=20°C; 0.5 h; 2: benzaldehyde in hexane T=0°C; 13 h; Product distribution / selectivity;
参考文献
US2011/295042 A1, ;
Page/Page column 5 ;
反应条件
lipase B from Candida antarctica in cyclohexane T=50°C; 0.75 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Li, Xiang; Shi, Yi; Wang, Zhoujun; Zhang, Yahong; Tang, Yi
Journal of Catalysis, 2012 , vol. 288, p. 24 - 32
反应条件
cells of Marchantia polymorpha in phosphate buffer; ethanol pH=6.0; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 21 p. 2365 - 2368
反应条件
potassium hydroxide; Ephedrine; [Ru(II)(η6-benzene)(μ-Cl)Cl]2 in isopropyl alcohol T=20°C; Title compound not separated from byproducts;
参考文献
Journal of Organometallic Chemistry, , vol. 690, # 13 p. 3176 - 3186
反应条件
4 A molecular sieve; subtilisin Carlsberg in 1,4-dioxane T=30°C; 48 h; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 127, # 35 p. 12228 - 12229
反应条件
Birman's catalyst; nicotinic anhydride in dichloromethane T=0°C; 12 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Shiina, Isamu; Nakata, Kenya; Ono, Keisuke; Mukaiyama, Teruaki
Helvetica Chimica Acta, 2012 , vol. 95, # 10 p. 1891 - 1911,21
Title/Abstract Full Text Show Details
Shiina, Isamu; Nakata, Kenya; Ono, Keisuke; Mukaiyama, Teruaki
Helvetica Chimica Acta, 2012 , vol. 95, # 10 p. 1891 - 1911
反应条件
Birman's catalyst; nicotinic anhydride in dichloromethane T=0°C; 12 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Shiina, Isamu; Nakata, Kenya; Ono, Keisuke; Mukaiyama, Teruaki
Helvetica Chimica Acta, 2012 , vol. 95, # 10 p. 1891 - 1911,21
Title/Abstract Full Text Show Details
Shiina, Isamu; Nakata, Kenya; Ono, Keisuke; Mukaiyama, Teruaki
Helvetica Chimica Acta, 2012 , vol. 95, # 10 p. 1891 - 1911
反应条件
Candida antarctica polyacrylamide-immobilized lipase B, Novozyme SP-435 in tert-butyl methyl ether T=28°C; 120 h; Inert atmosphereMolecular sieveEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Quijada, F. Javier; Gotor, Vicente; Rebolledo, Francisca
Organic Letters, 2010 , vol. 12, # 16 p. 3602 - 3605
反应条件
Aspergillus niger MTCC-404 T=35°C; 24 h; aq. phosphate bufferMicrobiological reactionClosed tube; optical yield given as percent ee;
参考文献
Yadav, Saroj; Yadav, Rama S.S.; Yadava, Sudha; Yadav, Kapil D.S.
Catalysis Communications, 2011 , vol. 12, # 9 p. 781 - 784
