1: tetrahydrofuran / 3 h / -10 °C 2: SiO2 3: oxone / tetrahydrofuran; H2O / 6 h / 0 °C 4: ethanol / 12 h / 68 °C 5: LDA / tetrahydrofuran / 2 h / 0 - 24 °C 6: Bu4NF / tetrahydrofuran / 7 h / 0 °C 7: MeI / acetonitrile / 1.5 h / 80 °C 8: aq. CuCl2 / tetrahydrofuran / 4 h / 23 °C 9: 2.) AcOH / 1.) THF, from -78 to 0 deg C, 12 h 10: H2 / Pd/C / ethyl acetate / 6 h / 23 °C / 2068.6 Torr 11: 69 percent / aq. NO(KSO3)2, KH2PO4 / acetone / 2 h / 23 °C View Scheme