反式-1,4-环己烷二甲酸单甲酯合成路线 （共 12 条）
反应条件
potassium hydroxide in methanol 5 h; Reflux;
参考文献
PIRAMAL LIFE SCIENCES LIMITED; SHARMA, Rajiv; KADAM, Kishorkumar Shivajirao; JADHAV, Ravindra Dnyandev; KANDRE, Shivaji Sadashiv; GUPTE, Amol
Patent: WO2012/29032 A2, 2012 ;
Location in patent: Example 129 ;
WO 2012/029032 A2
反应条件
aluminum oxide in cyclohexane; N,N-dimethyl-formamide study of selectivity of methylation on alumina surface; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 107, # 5 p. 1365 - 1369
反应条件
1: HCl 2: NaOH View Scheme
参考文献
Journal of Physical Chemistry, , vol. 97, # 37 p. 9280 - 9287
反应条件
1: hydrogen chloride; acetic acid / Hydrogenation.weiteres Reagens: Platin; Behandlung des Reaktionsprodukts mit warmer wss. Natronlauge oder warmer wss. Salzsaeure 2: sulfuric acid; methanol View Scheme
参考文献
Helvetica Chimica Acta, , vol. 21, p. 141
反应条件
sodium phosphate buffer; lipase from Candida rugosa 14 h; pH 7.2; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 37, # 50 p. 9029 - 9032
反应条件
methanol; sulfuric acid
参考文献
Helvetica Chimica Acta, , vol. 21, p. 141
反应条件
methanol; potassium hydroxide
参考文献
Helvetica Chimica Acta, , vol. 21, p. 141
反应条件
ultraviolettes Licht;
参考文献
Chemische Berichte, , vol. 47, p. 1805
参考文献
Fichter; Holbro
Helvetica Chimica Acta, 1938 , vol. 21, p. 141
反应条件
1.1: dimethylsulfide borane complex / tetrahydrofuran / 6 h / 0 - 20 °C 1.2: 1 h / 0 - 25 °C 2.1: Dess-Martin periodane / tetrahydrofuran / 3 h / 0 - 20 °C View Scheme
参考文献
MERCK SHARP and DOHME CORP.; HAIDLE, Andrew, M.; ALTMAN, Michael, D.; KATTAR, Solomon, D.; CHRISTOPHER, Matthew; ELLIS, John, Michael; FISCHER, Christian; NORTHRUP, Alan, B.; CHILDERS, Kaleen Konrad
Patent: WO2013/192088 A1, 2013 ;
