3,5-二-叔-丁基-4-甲氧基甲苯合成路线 （共 6 条）
反应条件
1: 2,6-di-tert-butyl-4-methyl-phenol With sodium hydride in tetrahydrofuran; mineral oil T=25°C; 2: dimethyl sulfate in tetrahydrofuran; mineral oil T=20°C; 2 h;
参考文献
Villalonga-Barber, Carolina; Meligova, Aggeliki K.; Alexi, Xanthippi; Steele, Barry R.; Kouzinos, Constantinos E.; Screttas, Constantinos G.; Katsanou, Efrosini S.; Micha-Screttas, Maria; Alexis, Michael N.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 1 p. 339 - 351
反应条件
potassium hydroxide in dimethyl sulfoxide T=100°C; 0.166667 h; Microwave irradiation;
参考文献
Pothi, Tejas; Dawange, Mahesh; Chavan, Kamlesh; Sharma, Rajiv; Deka, Nabajyoti
Journal of the Korean Chemical Society, 2012 , vol. 56, # 6 p. 706 - 711
反应条件
1: 1,3-di-tert-butyl-2-methoxy-5-methylbenzene With 4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran T=20°C; 1 h; Inert atmosphere; 2: carbon dioxide in tetrahydrofuran HeatingLarge scale reaction;
参考文献
Knorr, Rudolf; Rossmann, Eva Christine; Knittl, Monika
Synthesis, 2010 , # 13 art. no. C01110SS, p. 2124 - 2128
反应条件
4,4'-di-tert-butylbiphenyl; lithium Acidic conditions;
参考文献
Knorr, Rudolf; Rossmann, Eva Christine; Knittl, Monika
Synthesis, 2010 , # 13 art. no. C01110SS, p. 2124 - 2128
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
18 h; HeatingIrradiation;
参考文献
Campi, Eva M.; Gatehouse, Bryan M. K.; Jackson, W. Roy; Rae, Ian D.; Wong, Margaret G.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2566 - 2569
反应条件
1: 62 percent / N-bromosuccinimide, benzoyl peroxide / CCl4 / 18 h / Heating; Irradiation
2: 11.2 g / acetic acid / 9 h / Heating
3: 59 percent / sodium methoxide / methanol / 18 h / Ambient temperature
View Scheme
参考文献
Campi, Eva M.; Gatehouse, Bryan M. K.; Jackson, W. Roy; Rae, Ian D.; Wong, Margaret G.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2566 - 2569
