2-[2-(二甲胺基)乙氧基]苯甲醛合成路线 （共 6 条）
反应条件
hydrogenchloride; potassium carbonate in acetone
参考文献
Boehringer Ingelheim Pharma KG
Patent: US6255327 B1, 2001 ;
反应条件
sodium methylate; chlorobenzene
参考文献
Ahn, Gang; Schifano-Faux, Nadege; Goossens, Jean-Francois; Baldeyrou, Brigitte; Couture, Axel; Grandclaudon, Pierre; Lansiaux, Amelie; Ryckebusch, Adina
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 8 p. 2259 - 2263
反应条件
1: 78 percent / NaH / dimethylformamide; diethyl ether / 15 h / Ambient temperature 2: 1.) 1.5 M n-BuLi / 1.) hexane, ether, room temp., 2 h, 2.) hexane, ether, room temp., 0.5 h View Scheme
参考文献
Wada, Akimori; Kanatomo, Shoichi; Nagai, Sotoo
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1016 - 1022
反应条件
in N,N-dimethyl-formamide T=110°C; 2 h;
参考文献
Mukhopadhyay, Chhanda; Tapaswi, Pradip Kumar; Drew, Michael G.B.
Tetrahedron Letters, 2010 , vol. 51, # 30 p. 3944 - 3950
反应条件
n-butyllithium 1.) hexane, ether, room temp., 2 h, 2.) hexane, ether, room temp., 0.5 h; Yield given. Multistep reaction;
参考文献
Wada, Akimori; Kanatomo, Shoichi; Nagai, Sotoo
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1016 - 1022
反应条件
ethanol; ammonia; nickel Hydrogenation;
参考文献
Hoffmann-La Roche
Patent: US2879293 , 1957 ;
