3-甲氧基-N,N-二甲基苄胺合成路线 （共 19 条）
反应条件
potassium hydroxide in water T=80°C; 3 h; Green chemistry;
参考文献
Chen, Wen-Xin; Zhang, Cai-Yun; Lu, Jian-Mei
Journal of Chemical Research, 2013 , vol. 37, # 10 p. 611 - 614
反应条件
1: With titanium(IV) isopropylate in methanol T=20°C; Addition; 2: With sodium tetrahydroborate in methanol T=20°C; Reduction; 1.5 h;
参考文献
Bhattacharyya, Sukanta
Synthetic Communications, 2000 , vol. 30, # 11 p. 2001 - 2008
反应条件
dimethyl amine in palladium on activated carbon; diethyl ether; ethanol
参考文献
Eli Lilly and Company
Patent: US5747517 A1, 1998 ;
US 5747517 A
反应条件
dimethyl amine in water; acetonitrile
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1.) 0 deg C; 2.) rt, 30 min, reflux 2h;
参考文献
Yamagiwa, Yoshiro; Ohashi, Kinji; Sakamoto, Yoshitaka; Hirakawa, Shinji; Kamikawa, Tadao; Kubo, Isao
Tetrahedron, 1987 , vol. 43, # 15 p. 3387 - 3394
反应条件
1: With titanium(IV) isopropylate; triethylamine in ethanol T=25°C; 12 h; 2: With sodium tetrahydroborate in ethanol T=25°C; 12 h;
参考文献
Li, Hu; Cai, Gui-Xin; Shi, Zhang-Jie
Dalton Transactions, 2010 , vol. 39, # 43 p. 10442 - 10446
反应条件
in dichloromethane T=20°C; 24 h;
参考文献
Pereira, Junia M.; Severino, Richele P.; Vieira, Paulo C.; Fernandes, Joao B.; da Silva, M. Fatima G.F.; Zottis, Aderson; Andricopulo, Adriano D.; Oliva, Glaucius; Correa, Arlene G.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 19 p. 8889 - 8895
反应条件
1: CH2Cl2 / 1 h / Ambient temperature 2: 90 percent / lithium aluminium hydride / tetrahydrofuran / 1.) 0 deg C; 2.) rt, 30 min, reflux 2h View Scheme
参考文献
Tetrahedron, , vol. 43, # 15 p. 3387 - 3394
反应条件
1: thionyl chloride / 1 h / Ambient temperature 2: CH2Cl2 / 1 h / Ambient temperature 3: 90 percent / lithium aluminium hydride / tetrahydrofuran / 1.) 0 deg C; 2.) rt, 30 min, reflux 2h View Scheme
参考文献
Tetrahedron, , vol. 43, # 15 p. 3387 - 3394
反应条件
1: potassium hydroxide / water / 3 h / 100 °C / |Green chemistry 2: potassium hydroxide / water / 3 h / 80 °C / |Green chemistry View Scheme
参考文献
Tetrahedron, , vol. 70, # 4 p. 880 - 885
