1: Pd(OAc)4 / methanol; CH2Cl2 / 0.03 h / -15 °C 2: 1 M aq. HCl / tetrahydrofuran / 0.25 h / Ambient temperature 3: Et3N / tetrahydrofuran / 1.) room temp., 2.) room temp., 24 h 4: 97 percent / LiOH*H2O / methanol; H2O / 2.5 h / Heating View Scheme