(R)-(+)-2,2-二甲基-1,3-二氧戊环-4-甲醛合成路线 （共 94 条）
反应条件
sodium periodate; sodium hydrogencarbonate in dichloromethane 1 h;
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 29, # 2 p. 91 - 96
反应条件
sodium periodate; Dowex 50W(H(1+)) resin; sodium hydrogencarbonate 1.) DMF, RT, 24 h; 2.) H2O, RT, 1 h; Multistep reaction. Title compound not separated from byproducts;
参考文献
Carbohydrate Research, , vol. 138, p. 329 - 334
反应条件
sodium periodate; sodium hydrogencarbonate; toluene-4-sulfonic acid 1.) DMF, RT, 1 h; 2.) H2O, RT, 1 h; Multistep reaction. Further byproducts given. Title compound not separated from byproducts;
参考文献
Carbohydrate Research, , vol. 138, p. 329 - 334
反应条件
sodium periodate; sodium hydrogencarbonate; toluene-4-sulfonic acid 1.) DMF, RT, 1 h; 2.) H2O, RT, 1 h; Multistep reaction. Further byproducts given. Title compound not separated from byproducts;
参考文献
Carbohydrate Research, , vol. 138, p. 329 - 334
反应条件
in dichloromethane Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Wulff, Gunther; Hansen, Achim
Carbohydrate Research, 1987 , vol. 164, p. 123 - 140
反应条件
zinc 1) MeCN, 0 degC, 10 min; 2) MeCN, 0 degC, 2 h; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 29, # 15 p. 1803 - 1806
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Heathcock, Clayton H.; Pirrung, Michael C.; Lampe, John; Buse, Charles T.; Young, Steven D.
Journal of Organic Chemistry, 1981 , vol. 46, # 11 p. 2290 - 2300
反应条件
sulfuric acid in water T=45°C; 1.5 h;
参考文献
Fischer, Michael; Schmoelzer, Christoph; Nowikow, Christina; Schmid, Walther
European Journal of Organic Chemistry, 2011 , # 9 p. 1645 - 1651
反应条件
zinc 1) MeCN, 0 degC, 10 min; 2) MeCN, 0 degC, 2 h; Yield given. Multistep reaction;
参考文献
Kitagawa, Osamu; Taguchi, Takeo; Kobayashi, Yoshiro
Tetrahedron Letters, 1988 , vol. 29, # 15 p. 1803 - 1806
反应条件
1: With iodine; zinc in tetrahydrofuran T=5 - 10°C; 24 h; Ultrasonic irradiation; 2: With water; ammonium chloride
参考文献
PHARMAESSENTIA CORP.
Patent: WO2006/119347 A1, 2006 ;
Location in patent: Page/Page column 9-10 ;
