3-甲基-2-(3-甲基-2-丁烯基)呋喃合成路线 （共 37 条）
反应条件
1: Pd/Cu
2: 77 percent / KI / PdI2 / N,N-dimethyl-acetamide / 24 h / 100 °C
View Scheme
参考文献
Gabriele; Salerno; Lauria
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 7687 - 7692
反应条件
1: 79 percent / Pd(PPh3)4 / N,N-dimethyl-acetamide / 16 h / 90 °C
2: 70 percent / PdCl2[P(o-Tol)3]2 / N,N-dimethyl-acetamide / 20 h / 90 °C
3: NaOH / H2O / 4 h / Heating
4: Cu / quinoline / 180 °C
View Scheme
参考文献
Bach, Thorsten; Krueger, Lars
European Journal of Organic Chemistry, 1999 , # 9 p. 2045 - 2057
反应条件
quinoline; copper
Heating;
参考文献
Bach; Krueger
Synlett, 1998 , # 11 p. 1185 - 1186
反应条件
1: 81 percent / aq. H2SO3 / 2 h / 50 °C
2: Pd/Cu
3: 77 percent / KI / PdI2 / N,N-dimethyl-acetamide / 24 h / 100 °C
View Scheme
参考文献
Gabriele; Salerno; Lauria
Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 7687 - 7692
反应条件
1: 69 percent / ammonium hexafluorophosphate / CpRu(Ph3P)2Cl / 5 h / 100 °C
2: 1.) OsO4, N-methylmorpholine, 2.) p-toluenesulfonic acid hydrate / 1.) THF, t-BuOH, H2O, r.t., 14 h, 2.) r.t., 12 h
3: 88 percent / LiOH / methanol; H2O / 18 h / Ambient temperature
4: 54 percent / dimethylsulfoxide / 24 h / 160 °C
View Scheme
参考文献
Trost, Barry M.; Flygare, John A.
Journal of Organic Chemistry, 1994 , vol. 59, # 5 p. 1078 - 1082
反应条件
diisobutylaluminium hydride in toluene
T=-15°C; Yield given;
参考文献
Takano, Seiichi; Morimoto, Masamichi; Satoh, Shigeki; Ogasawara, Kunio
Chemistry Letters, 1984 , p. 1261 - 1262
反应条件
n-butyllithium in tetrahydrofuran; hexane
1.) -78 deg C, 45 min, 2.) -78 deg C, 90 min;
参考文献
Weyerstahl, Peter; Schenk, Anja; Marschall, Helga
Liebigs Annalen, 1995 , # 10 p. 1849 - 1854
反应条件
1: 87 percent / BuLi / tetrahydrofuran / -10 °C
2: 68 percent / Raney Ni / ethanol / 0.5 h
View Scheme
参考文献
Okazaki, Renji; Negishi, Yoshio; Inamoto, Naoki
Journal of the Chemical Society, Chemical Communications, 1982 , # 18 p. 1055 - 1056
反应条件
1: Florisil chromatography
2: 87 percent / BuLi / tetrahydrofuran / -10 °C
3: 68 percent / Raney Ni / ethanol / 0.5 h
View Scheme
参考文献
Okazaki, Renji; Negishi, Yoshio; Inamoto, Naoki
Journal of the Chemical Society, Chemical Communications, 1982 , # 18 p. 1055 - 1056
反应条件
1: 87.5 percent / NaBH4 / ethanol / 0 °C
2: pyridinium p-toluenesulfonate
3: 55 percent
4: 88.9 percent / pyridinium chlorochromate
5: 100 percent / 0.2percent p-toluenesulfonic acid / tetrahydrofuran; H2O / 8 h / 65 °C
6: 100 percent / 0.8percent formic acid / CDCl3 / 168 h / 55 °C
View Scheme
参考文献
Iriye, Ryozo; Uno, Tsuyoshi; Ohwa, Ikuo; Konishi, Asako
Agricultural and Biological Chemistry, 1990 , vol. 54, # 7 p. 1841 - 1843
