3-甲基-2-(3-甲基-2-丁烯基)呋喃合成路线 （共 37 条）
反应条件
1: pyridinium p-toluenesulfonate
2: 55 percent
3: 88.9 percent / pyridinium chlorochromate
4: 100 percent / 0.2percent p-toluenesulfonic acid / tetrahydrofuran; H2O / 8 h / 65 °C
5: 100 percent / 0.8percent formic acid / CDCl3 / 168 h / 55 °C
View Scheme
参考文献
Iriye, Ryozo; Uno, Tsuyoshi; Ohwa, Ikuo; Konishi, Asako
Agricultural and Biological Chemistry, 1990 , vol. 54, # 7 p. 1841 - 1843
反应条件
pyridinium p-toluenesulfonate in dichloromethane
6 h; Heating;
参考文献
Iriye, Ryozo; Uno, Tsuyoshi; Ohwa, Ikuo; Konishi, Asako
Agricultural and Biological Chemistry, 1990 , vol. 54, # 7 p. 1841 - 1843
反应条件
1: 1.) OsO4, N-methylmorpholine, 2.) p-toluenesulfonic acid hydrate / 1.) THF, t-BuOH, H2O, r.t., 14 h, 2.) r.t., 12 h
2: 88 percent / LiOH / methanol; H2O / 18 h / Ambient temperature
3: 54 percent / dimethylsulfoxide / 24 h / 160 °C
View Scheme
参考文献
Trost, Barry M.; Flygare, John A.
Journal of Organic Chemistry, 1994 , vol. 59, # 5 p. 1078 - 1082
反应条件
1: 88 percent / LiOH / methanol; H2O / 18 h / Ambient temperature
2: 54 percent / dimethylsulfoxide / 24 h / 160 °C
View Scheme
参考文献
Trost, Barry M.; Flygare, John A.
Journal of Organic Chemistry, 1994 , vol. 59, # 5 p. 1078 - 1082
反应条件
1: 1.) n-BuLi
2: 72 percent / TBAF, HOAc / tetrahydrofuran
3: LDA / tetrahydrofuran
4: NaBH4
5: DMF dineopentyl acetal / CHCl3 / Heating
View Scheme
参考文献
Marshall, James A.; DuBay, William J.
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3602 - 3603
反应条件
1: LDA / tetrahydrofuran
2: NaBH4
3: DMF dineopentyl acetal / CHCl3 / Heating
View Scheme
参考文献
Marshall, James A.; DuBay, William J.
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3602 - 3603
反应条件
1: 72 percent / TBAF, HOAc / tetrahydrofuran
2: LDA / tetrahydrofuran
3: NaBH4
4: DMF dineopentyl acetal / CHCl3 / Heating
View Scheme
参考文献
Marshall, James A.; DuBay, William J.
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3602 - 3603
反应条件
1: 69 percent / NaOMe / methanol; tetrahydrofuran
2: LDA / tetrahydrofuran
3: NaBH4
4: DMF dineopentyl acetal / CHCl3 / Heating
View Scheme
参考文献
Marshall, James A.; DuBay, William J.
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3602 - 3603
反应条件
1: 1) n-BuLi / THF, hexane
2: 68 percent / Raney Ni / acetone; ethanol / 0.5 h / Ambient temperature
View Scheme
参考文献
Okazaki, Renji; Negishi, Yoshio; Inamoto, Naoki
Journal of Organic Chemistry, 1984 , vol. 49, # 20 p. 3819 - 3824
反应条件
N,N-dimethylformamide dineopentyl acetal in chloroform
Heating; Yield given. Yields of byproduct given;
参考文献
Marshall, James A.; DuBay, William J.
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3602 - 3603
