(R)-(+)-甲基对甲苯亚砜合成路线 （共 72 条）
反应条件
titanium(IV) isopropylate; dihydrogen peroxide in dichloromethane; water T=0°C; 10 h; Inert atmosphere; optical yield given as percent eeenantioselective reaction;
参考文献
Journal of Molecular Catalysis A: Chemical, , vol. 361-362, p. 36 - 44
反应条件
in diethyl ether Ambient temperature;
参考文献
Andersen, Kenneth K.; Bujnicki, Bogdan; Drabowicz, Jozef; Mikolajczyk, Marian; O'Brien, John B.
Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 4070 - 4072
反应条件
1.1: LiHMDS / tetrahydrofuran / 1.5 h / 20 °C 1.2: tetrahydrofuran / 2 h / -78 - 20 °C 1.3: 61 percent / LiHMDS / tetrahydrofuran / 0.67 h / -78 - -45 °C 2.1: 97 percent / diethyl ether; tetrahydrofuran / 0.5 h / -78 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 20 p. 7559 - 7567
反应条件
1: 89 percent / LiHMDS / tetrahydrofuran / 0.33 h / -78 °C 2: 97 percent / diethyl ether; tetrahydrofuran / 0.5 h / -78 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 20 p. 7559 - 7567
反应条件
1: 93 percent / LiHMDS / tetrahydrofuran / 0.5 h / -78 °C 2: diethyl ether; tetrahydrofuran / -78 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 64, # 20 p. 7559 - 7567
反应条件
1: (-)-quinine With thionyl chloride; triethylamine in tetrahydrofuran T=-78°C; 0.5 h; 2: p-tolyldiethylaluminum in tetrahydrofuran T=-78°C; 2 h; 3: methyl-magnesium chloride in tetrahydrofuran T=0°C; 0.5 h; Product distribution / selectivity;
参考文献
APSINTERM LLC
Patent: JP2005/522525 A, 2005 ;
Location in patent: Page/Page column 56-57 ;
反应条件
1: SOCl2 / benzene / 0 °C 2: pyridine / diethyl ether / 1 h / Ambient temperature 3: 1.) Mg / 1.) ether, 2.) benzene, room temp., 2 h View Scheme
参考文献
Synthesis, , # 2 p. 173
反应条件
(R,R)-Ph-PyBOX; iron tris(.gamma.-chloroacetylacetonate) in acetone T=-20°C; 24 h; Resolution of racemate; stereoselective reaction;
参考文献
Chemistry - A European Journal, , vol. 20, # 4 p. 966 - 969
反应条件
in tetrahydrofuran; toluene T=-30°C; 0.25 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 8, # 4 p. 591 - 598
反应条件
in tetrahydrofuran; toluene T=-30°C; 0.25 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 8, # 4 p. 591 - 598
