magnesium bromide T=20°C; Strecker reaction; 0.0833333 h;

in butan-1-ol T=200°C; decarboxylative Strecker reaction; 0.166667 h; Microwave irradiation; regioselective reaction;

2-ethyl-1-hexanoic acid in toluene T=200°C; 0.333333 h; Microwave irradiationSealed tube; Overall yield = 67 percent; regioselective reaction;

1.1: copper(II) bis(trifluoromethanesulfonate) / dichloromethane / 0.25 h / 20 °C 1.2: 18 h / 20 °C 2.1: 2-ethyl-1-hexanoic acid / toluene / 0.33 h / 200 °C / |Microwave irradiation; |Sealed tube View Scheme

T=70°C; 20 h; Mechanism;