(1S,2R)-N-BOC-1-氨基-2-苯基环丙烷羧酸合成路线 （共 8 条）
反应条件
lithium hydroxide in methanol; water 2.5 h; Heating;
参考文献
Williams, Robert M.; Fegley, Glenn J.
Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6933 - 6935
反应条件
1: 2-methyl-propan-2-ol; hexane / Heating 2: aq. LiOH / methanol / Heating View Scheme
参考文献
Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J.
Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907
反应条件
1: 2-methyl-propan-2-ol; hexane / Heating 2: aq. LiOH / methanol / Heating View Scheme
参考文献
Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J.
Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907
反应条件
1: Et3N, diphenylphosphoryl azide / 2-methyl-propan-2-ol; hexane / Heating 2: 2-methyl-propan-2-ol; hexane / Heating 3: aq. LiOH / methanol / Heating View Scheme
参考文献
Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J.
Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907
反应条件
1: 91 percent / K2CO3 2: 73 percent / aq. NaOH / methanol 3: Et3N, diphenylphosphoryl azide / 2-methyl-propan-2-ol; hexane / Heating 4: 2-methyl-propan-2-ol; hexane / Heating 5: aq. LiOH / methanol / Heating View Scheme
参考文献
Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J.
Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907
反应条件
1: 73 percent / aq. NaOH / methanol 2: Et3N, diphenylphosphoryl azide / 2-methyl-propan-2-ol; hexane / Heating 3: 2-methyl-propan-2-ol; hexane / Heating 4: aq. LiOH / methanol / Heating View Scheme
参考文献
Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J.
Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907
反应条件
1: 1 M aq. HCl / tetrahydrofuran / 0.25 h / Ambient temperature 2: Et3N / tetrahydrofuran / 1.) room temp., 2.) room temp., 24 h 3: 97 percent / LiOH*H2O / methanol; H2O / 2.5 h / Heating View Scheme
参考文献
Williams, Robert M.; Fegley, Glenn J.
Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6933 - 6935
反应条件
1: Pd(OAc)4 / methanol; CH2Cl2 / 0.03 h / -15 °C 2: 1 M aq. HCl / tetrahydrofuran / 0.25 h / Ambient temperature 3: Et3N / tetrahydrofuran / 1.) room temp., 2.) room temp., 24 h 4: 97 percent / LiOH*H2O / methanol; H2O / 2.5 h / Heating View Scheme
参考文献
Williams, Robert M.; Fegley, Glenn J.
Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6933 - 6935
