(S)-3-Z-氨基-1-重氮基-3-苯基-2-丁酮合成路线 （共 16 条）
反应条件
1: 58 percent / HCl / tetrahydrofuran 2: 90 percent / HBr / acetic acid View Scheme
参考文献
Fittkau, Siegfried; Jahreis, Guenther; Peters, Klaus; Balaspiri, Lajos
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 4 p. 529 - 538
反应条件
1: HCl / dioxane; diethyl ether / 1 h / 0 °C 2: NaBH4 / tetrahydrofuran; H2O / 0.75 h / 0 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 12 p. 1758 - 1768
反应条件
1: 63 percent / silver benzoate, Et3N / 0.5 h / Ambient temperature 2: 93 percent / H2 / 20percent Pd(OH)2/C / methanol / 7 h / 760 Torr / Ambient temperature View Scheme
参考文献
Buchschacher; Cassal; Furst; Meier
Helvetica Chimica Acta, 1977 , vol. 60, # 8 p. 2747 - 2755
反应条件
1: 82 percent / HBr 2: 45 percent / NaBH4 View Scheme
参考文献
Albeck, Amnon; Persky, Rachel
Tetrahedron, 1994 , vol. 50, # 21 p. 6333 - 6346
反应条件
hydrogenchloride in tetrahydrofuran
参考文献
Fittkau, Siegfried; Jahreis, Guenther; Peters, Klaus; Balaspiri, Lajos
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 4 p. 529 - 538
反应条件
1: 63 percent / silver benzoate, Et3N / 0.5 h / Ambient temperature
2: 93 percent / H2 / 20percent Pd(OH)2/C / methanol / 7 h / 760 Torr / Ambient temperature
View Scheme
参考文献
Buchschacher; Cassal; Furst; Meier
Helvetica Chimica Acta, 1977 , vol. 60, # 8 p. 2747 - 2755
