1: 75 percent / n-BuLi / tetrahydrofuran / -78 °C 2: 87 percent / HF, splinters of glass / acetonitrile / 0 °C 3: 78 percent / Dess-Martin periodinane / CH2Cl2 / 1 h / Ambient temperature 4: 83 percent / NaNH2 / tetrahydrofuran / 0.33 h / Ambient temperature 5: 99 percent / TBAF, 4 Angstroem molecular sieves / tetrahydrofuran / -78 °C 6: 80 percent / DCC, 4-DMAP / CH2Cl2 / 12 h / Ambient temperature 7: 94 percent / <RuCHPh>Cl2*(PCy3)2 / CH2Cl2 / 12 h / Ambient temperature 8: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 9: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

1: 88 percent / PPTS / methanol / 36 h / Ambient temperature 2: 96 percent / 2,6-lutidine / CH2Cl2 / -78 °C 3: 82 percent / CSA / methanol; CH2Cl2 / 5 h / 0 °C 4: 79 percent / PDC / dimethylformamide / 36 h / Ambient temperature 5: 80 percent / DCC, 4-DMAP / CH2Cl2 / 12 h / Ambient temperature 6: 94 percent / <RuCHPh>Cl2*(PCy3)2 / CH2Cl2 / 12 h / Ambient temperature 7: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 8: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

1: 87 percent / HF, splinters of glass / acetonitrile / 0 °C 2: 78 percent / Dess-Martin periodinane / CH2Cl2 / 1 h / Ambient temperature 3: 83 percent / NaNH2 / tetrahydrofuran / 0.33 h / Ambient temperature 4: 99 percent / TBAF, 4 Angstroem molecular sieves / tetrahydrofuran / -78 °C 5: 80 percent / DCC, 4-DMAP / CH2Cl2 / 12 h / Ambient temperature 6: 94 percent / <RuCHPh>Cl2*(PCy3)2 / CH2Cl2 / 12 h / Ambient temperature 7: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 8: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

1: 79 percent / PDC / dimethylformamide / 36 h / Ambient temperature 2: 80 percent / DCC, 4-DMAP / CH2Cl2 / 12 h / Ambient temperature 3: 94 percent / <RuCHPh>Cl2*(PCy3)2 / CH2Cl2 / 12 h / Ambient temperature 4: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 5: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

1: 80 percent / DCC, 4-DMAP / CH2Cl2 / 12 h / Ambient temperature 2: 94 percent / <RuCHPh>Cl2*(PCy3)2 / CH2Cl2 / 12 h / Ambient temperature 3: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 4: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

1: 82 percent / CSA / methanol; CH2Cl2 / 5 h / 0 °C 2: 79 percent / PDC / dimethylformamide / 36 h / Ambient temperature 3: 80 percent / DCC, 4-DMAP / CH2Cl2 / 12 h / Ambient temperature 4: 94 percent / <RuCHPh>Cl2*(PCy3)2 / CH2Cl2 / 12 h / Ambient temperature 5: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 6: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

1: 99 percent / TBAF, 4 Angstroem molecular sieves / tetrahydrofuran / -78 °C 2: 80 percent / DCC, 4-DMAP / CH2Cl2 / 12 h / Ambient temperature 3: 94 percent / <RuCHPh>Cl2*(PCy3)2 / CH2Cl2 / 12 h / Ambient temperature 4: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 5: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

1: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 2: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

暂无反应条件数据

bis(cyclopentadienyl)titanium dichloride; magnesium in tetrahydrofuran deoxygenation;