1: 98.8 percent / H2 / Pd/C / methanol / 24 h / 30 °C / 7500.6 Torr 2: 99 percent / PTSA / methanol / 4 h / 40 °C 3: 67.4 percent / Bu2SnO; Et3N / CH2Cl2 / 0 - 20 °C 4: 99.5 percent / imidazole; Et3N / dimethylformamide / 1.33 h / 0 - 20 °C 5: 89 percent / NaI; pyridine / dimethylformamide / 2.5 h / 75 - 80 °C 6: 99 percent / LiOH*H2O / methanol; H2O / 8 h View Scheme

1.1: 98 percent / H2 / Pd/C / methanol / 8 h / 20 °C 2.1: 97 percent / aq. HCl / methanol / 1 h / 20 °C 3.1: 75 percent / pyridine / 12 h / -17 °C 4.1: 89 percent / ethanol; H2O / 12 h / 20 °C 5.1: Zn / tetrahydrofuran / 0.17 h / 50 °C / ultrasonic irradiation 5.2: 69 percent / tetrahydrofuran / 5.5 h / 50 °C / ultrasonic irradiation 6.1: 84 percent / p-toluenesulfonic acid / CH2Cl2 / 2 h / 20 °C View Scheme

1.1: 98 percent / H2 / Pd/C / methanol / 8 h / 20 °C 2.1: 97 percent / aq. HCl / methanol / 1 h / 20 °C 3.1: 75 percent / pyridine / 12 h / -17 °C 4.1: 89 percent / ethanol; H2O / 12 h / 20 °C 5.1: Zn / tetrahydrofuran / 0.17 h / 50 °C / ultrasonic irradiation 5.2: 69 percent / tetrahydrofuran / 5.5 h / 50 °C / ultrasonic irradiation 6.1: 84 percent / p-toluenesulfonic acid / CH2Cl2 / 2 h / 20 °C 7.1: 86 percent / K2CO3 / acetone / 20 h / 20 °C View Scheme