2-(4-溴苯基)-N,N-二甲基乙胺合成路线 （共 5 条）
反应条件
1: With methanol; sodium tris(acetoxy)borohydride; acetic acid T=20°C; 1 h; 2: With water; sodium hydrogencarbonate in methanol
参考文献
Meiji Seika Kaisha Ltd.
Patent: EP2151447 A1, 2010 ;
Location in patent: Page/Page column 38 ;
反应条件
in tetrahydrofuran T=45°C; 48 h; Inert atmosphere;
参考文献
Sowa, Sylwia; Muehlberg, Michaela; Pietrusiewicz, K. Michal; Hackenberger, Christian P.R.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 12 p. 3465 - 3472
参考文献
Sowa, Sylwia; Muehlberg, Michaela; Pietrusiewicz, K. Michal; Hackenberger, Christian P.R.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 12 p. 3465 - 3472
反应条件
1.1: n-butyllithium / diethyl ether; hexane / 3 h / -40 - 20 °C / |Inert atmosphere 1.2: 1 h / -40 - 20 °C / |Inert atmosphere 2.1: triethylamine / dichloromethane / 48 h / 0 - 20 °C / |Inert atmosphere 3.1: tetrahydrofuran / 48 h / 45 °C / |Inert atmosphere View Scheme
参考文献
Sowa, Sylwia; Muehlberg, Michaela; Pietrusiewicz, K. Michal; Hackenberger, Christian P.R.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 12 p. 3465 - 3472
参考文献
Auweraer, M. Van der; Viaene, L.; Haver, Ph. Van; Schryver, F. C. De
Journal of Physical Chemistry, 1993 , vol. 97, # 28 p. 7178 - 7184
