4,4,4-三氟-3-羟基-1-苯基丁烷-1-酮合成路线 （共 23 条）
反应条件
hydrogenchloride in ethanol 14 h; Heating;
参考文献
Xu, Yuelian; Dolbier Jr., William R.
Tetrahedron Letters, 1998 , vol. 39, # 50 p. 9151 - 9154
参考文献
Funabiki, Kazumasa; Matsunaga, Kei; Nojiri, Miwa; Hashimoto, Wataru; Yamamoto, Hitoshi; Shibata, Katsuyoshi; Matsui, Masaki
Journal of Organic Chemistry, 2003 , vol. 68, # 7 p. 2853 - 2860
参考文献
Funabiki, Kazumasa; Murase, Yoshihiro; Furuno, Yudai; Kubota, Yasuhiro; Ebihara, Masahiro; Matsui, Masaki
Tetrahedron, 2010 , vol. 66, # 18 p. 3283 - 3289
参考文献
Funabiki, Kazumasa; Murase, Yoshihiro; Furuno, Yudai; Kubota, Yasuhiro; Ebihara, Masahiro; Matsui, Masaki
Tetrahedron, 2010 , vol. 66, # 18 p. 3283 - 3289
反应条件
1.1: hexane / 1 h / Heating 2.1: H2O / hexane / 1 h / Heating 2.2: 90 percent / SiO2 / ethyl acetate; hexane View Scheme
参考文献
Funabiki, Kazumasa; Matsunaga, Kei; Matsui, Masaki; Shibata, Katsuyoshi
Synlett, 1999 , # 9 p. 1477 - 1479
反应条件
pyrrolidine in tetrahydrofuran 24 h; Heating;
参考文献
Zhang, Fanglin; Peng, Yiyuan; Liao, Saihu; Gong, Yuefa
Tetrahedron, 2007 , vol. 63, # 22 p. 4636 - 4641
反应条件
piperidine in methanol
参考文献
Dorai,C.S.; Damodaran,V.
Indian Journal of Chemistry, 1975 , vol. 13, p. 854 - 855
反应条件
lithium diisopropyl amide 1.) THF, -50 deg C, 30 min, 2.) THF, 0 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Lin, Jenq Tain; Yamazaki, Takashi; Kitazume, Tomoya
Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3211 - 3217
反应条件
sodium tetrahydroborate in ethanol 4 h; Ambient temperature; Yields of byproduct given;
参考文献
Ratner, V. G.; Pashkevich, K. I.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 6.1 p. 1046 - 1049
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 6 p. 1212 - 1215
反应条件
catalytic reduction;
参考文献
Kawase, Masami; Sakagami, Hiroshi; Kusama, Kaoru; Motohashi, Noboru; Saito, Setsuo
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 21 p. 3113 - 3118
