反应条件
1: 1) Mg / 1) Et2O, toluene, 2) toluene, 2 h, reflux 2: KOH / bis-(2-hydroxy-ethyl) ether / 1.5 h / 210 °C View Scheme
参考文献
Cami-Kobeci, Gerta; Polgar, Willma E.; Khroyan, Taline V; Toll, Lawrence; Husbands, Stephen M.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6531 - 6537
