1-(苄氧基)-2,4-二氟苯合成路线 （共 3 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
PLEXXIKON, INC.
Patent: WO2007/2325 A1, 2007 ;
Location in patent: Page/Page column 142 ;
WO 2007/002325 A1
反应条件
potassium carbonate in acetone Heating;
参考文献
Chen, George T.; King, Michael; Gusovsky, Fabian; Creveling, Cyrus R.; Daly, John W.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 24 p. 3947 - 3955
反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -75 deg C, 30 min, 2.) THF, hexane, a) -75 deg C, 15 min, b) from -75 deg C to RT, 30 min 2: 0.14 g / Et3N, H2 / 15percent Pd/C / methanol View Scheme
参考文献
Chen, George T.; King, Michael; Gusovsky, Fabian; Creveling, Cyrus R.; Daly, John W.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 24 p. 3947 - 3955
