(S)-(+)-1,2-丙二胺-N,N,N',N'-四乙酸合成路线 (共 3 条)
反应条件
1: With sodium hydroxide in water T=15 - 45°C; 2: With sulfuric acid in water T=0°C; pH=1.5;
参考文献
US2010/152447 A1, ;
Page/Page column 2-3 ;
反应条件
1: (S)-(-)-1,2-diaminopropane dihydrochloride; chloroacetic acid With sodium hydroxide in water T=45°C; Industry scale; 2: methanol With sulfuric acid 6 h; RefluxIndustry scale;
参考文献
US2010/152447 A1, ;
Page/Page column 5 ;
参考文献
Journal of the American Chemical Society, , vol. 81, p. 2955