反应条件
1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) DMF, RT, 1 h 2: 93 percent / gas. HBr / CH2Cl2 / 4 h / 0 °C 4: CH2Cl2 / 0.5 h / Ambient temperature 5: aq. HCl / ethyl acetate / 3 h View Scheme
参考文献
Semple, Graeme; Ryder, Hamish; Rooker, David P.; Batt, Andrzej R.; Kendrick, David A.; Szelke, Michael; Ohta, Mitsuaki; Satoh, Masato; Nishida, Akito; Akuzawa, Shinobu; Miyata, Keiji
Journal of Medicinal Chemistry, 1997 , vol. 40, # 3 p. 331 - 341
