5-溴-3-甲氧基-2-硝基吡啶合成路线 （共 5 条）
反应条件
sulfuric acid; nitric acid in water T=0°C; 20 h;
参考文献
Satoh, Motohide; Aramaki, Hisateru; Nakamura, Hiroshi; Inoue, Masafumi; Kawakami, Hiroshi; Shinkai, Hisashi; Matsuzaki, Yuji; Yamataka, Kazunobu
Patent: US2006/84665 A1, 2006 ;
Location in patent: Page/Page column 70 ;
反应条件
1: 50 percent / dimethylformamide / 2 h / 75 °C 2: 53 percent / H2SO4, HNO3 / 1.5 h / 100 °C View Scheme
参考文献
Acta Chemica Scandinavica, , vol. 47, # 8 p. 805 - 812
反应条件
1: With iron; acetic acid 2.5 h; 2: With sodium carbonate in water; ethyl acetate
参考文献
NOVARTIS AG; HUANG, Zilin; SENDZIK, Martin
Patent: WO2010/100127 A1, 2010 ;
Location in patent: Page/Page column 69-70 ;
WO 2010/100127 A1
反应条件
1: 95 percent / (PPh3)4Pd, Na2CO3 / benzene; ethanol / 2 h / Heating 2: 72 percent / ethanol; H2O / 3 h / Heating 3: 1.) H2 / Raney Ni / 1.) RT, 1 atm, 2.) 200 deg C, 3 h View Scheme
参考文献
Linstroem, Stefan; Eriksson, Mikael; Grivas, Spiros
Acta Chemica Scandinavica, 1993 , vol. 47, # 8 p. 805 - 812
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran; N,N-dimethyl-formamide
T=70°C; 15 h;
参考文献
Satoh, Motohide; Aramaki, Hisateru; Nakamura, Hiroshi; Inoue, Masafumi; Kawakami, Hiroshi; Shinkai, Hisashi; Matsuzaki, Yuji; Yamataka, Kazunobu
Patent: US2006/84665 A1, 2006 ;
Location in patent: Page/Page column 70 ;
