(2R,3R)-2-铵基-3-羟基-2-甲基丁酸酯合成路线 （共 4 条）
反应条件
hydrogenchloride 18 h; Heating;
参考文献
Watts, John; Benn, Alex; Flinn, Nick; Monk, Tracy; Ramjee, Manoj; Ray, Peter; Wang, Yikang; Quibell, Martin
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 11 p. 2903 - 2925
反应条件
1: n-Bu4NBH4 / methanol / -78 °C 2: 88 percent / NaH / dimethylformamide / 6 h / 0 °C 3: 80 percent / HCl / tetrahydrofuran; H2O / 2 h / 25 °C 4: Jones reagent / acetone / 5 h / 0 - 25 °C 5: 60 mg / HCl / H2O / 48 h / 100 °C View Scheme
参考文献
Avenoza, Alberto; Busto, Jesus H.; Corzana, Francisco; Peregrina, Jesus M.; Sucunza, David; Zurbano, Maria M.
Tetrahedron Asymmetry, 2004 , vol. 15, # 4 p. 719 - 724
反应条件
1: Jones reagent / acetone / 5 h / 0 - 25 °C 2: 60 mg / HCl / H2O / 48 h / 100 °C View Scheme
参考文献
Avenoza, Alberto; Busto, Jesus H.; Corzana, Francisco; Peregrina, Jesus M.; Sucunza, David; Zurbano, Maria M.
Tetrahedron Asymmetry, 2004 , vol. 15, # 4 p. 719 - 724
反应条件
1: 80 percent / HCl / tetrahydrofuran; H2O / 2 h / 25 °C 2: Jones reagent / acetone / 5 h / 0 - 25 °C 3: 60 mg / HCl / H2O / 48 h / 100 °C View Scheme
参考文献
Avenoza, Alberto; Busto, Jesus H.; Corzana, Francisco; Peregrina, Jesus M.; Sucunza, David; Zurbano, Maria M.
Tetrahedron Asymmetry, 2004 , vol. 15, # 4 p. 719 - 724
