(2-氯-6-甲基吡啶-4-基)甲醇合成路线 （共 6 条）
反应条件
1: With borane-THF in tetrahydrofuran T=0 - 20°C; 49 h; 2: With hydrogenchloride in tetrahydrofuran; water T=0°C; 0.5 h; 3: With sodium hydroxide in tetrahydrofuran; water
参考文献
Guo, Hongyan; Kim, Choung U.; Kim, Hae Soo; Lee, Chong-Kyo; Lee, Ill Young; Mitchell, Michael L.; Son, Jong Chan; Xu, Lianhong
Patent: US2008/70920 A1, 2008 ;
Location in patent: Page/Page column 37 ;
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 2.4 h; 2: With water in tetrahydrofuran
参考文献
Schering Corporation
Patent: US2007/167435 A1, 2007 ;
Location in patent: Page/Page column 32-33 ;
US 20070167435 A1
反应条件
acetic acid in tetrahydrofuran
参考文献
Zeneca Limited; Zeneca Pharma S. A.
Patent: US6362336 B1, 2002 ;
Location in patent: Example 43 ;
US 6362336 B1
参考文献
Bilodeau, Mark T.; Hartman, George D.
Patent: US2003/100567 A1, 2003 ;
反应条件
manganese(IV) oxide in chloroform T=20°C; 144 h;
参考文献
WO2010/11657 A1, ;
Page/Page column 41 ;
WO 2010/011657 A1
反应条件
1: With hydrogen; triethylamine; palladium 10 on activated carbon in ethyl acetate P=760.051 Torr; 21 h; 2: With hydrogen; palladium(II) hydroxide/carbon in ethyl acetate 5 h;
参考文献
Bamberg, Joe Timothy; Gabriel, Tobias; Krauss, Nancy Elisabeth; Mirzadegan, Taraneh; Palmer, Wylie Solang; Smith, David Bernard
Patent: US2004/77646 A1, 2004 ;
Location in patent: Page 116 ;
