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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
15288-01-4
合成路线
(共 8 条)
13575-75-2
6,7-二甲氧基-3,4-二氢-2H-1-萘酮
→
反应条件
15288-01-4
反应条件
[TMAH][Al2Cl7] in dichloromethane Heating;
参考文献
N.V. Organon
Patent: US2011/28451 A1, 2011 ;
US 20110028451 A1
→
反应条件
15288-01-4
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide T=20°C; 2 h; 2: With hydrogenchloride in water; N,N-dimethyl-formamide pH=4;
参考文献
N.V. ORGANON; TIMMERS, Cornelis, Marius; LOOZEN, Hubert, Jan, Jozef
Patent: WO2011/12674 A1, 2011 ;
Location in patent: Page/Page column 18; 19 ;
WO 2011/012674 A1
→
反应条件
15288-01-4
反应条件
urea; sodium nitrite in sulfuric acid; water
参考文献
Pinney, Kevin G.; Mocharla, Vani P.; Chen, Zhi; Garner, Charles M.; Ghatak, Anjan; Hadimani, Mallinath; Kessler, Jimmy; Dorsey, James M.; Edvardsen, Klaus; Chaplin, David J.; Prezioso, Joseph; Ghatak, Usha R.
Patent: US2004/43969 A1, 2004 ;
120-14-9
3,4-二甲氧基苯甲醛
→
反应条件
15288-01-4
反应条件
1: 95 percent / NaH / tetrahydrofuran; dimethylsulfoxide / 20 h / Ambient temperature 2: 95 percent / H2 / Pd/C 3: 93 percent / polyphosphoric acid / 4 h / 40 °C 4: 40 percent / HBr View Scheme
参考文献
Beugelmans, Rene; Chastanet, Jacqueline; Ginsburg, Helene; Quintero-Cortes, Leticia; Roussi, Georges
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4933 - 4938
→
反应条件
15288-01-4
反应条件
in 1,4-dioxane; water; ethyl acetate
参考文献
The Research Foundation of State University of New York
Patent: US6284789 B1, 2001 ;
98799-43-0
→
反应条件
15288-01-4
反应条件
1: 95 percent / H2 / Pd/C 2: 93 percent / polyphosphoric acid / 4 h / 40 °C 3: 40 percent / HBr View Scheme
参考文献
Beugelmans, Rene; Chastanet, Jacqueline; Ginsburg, Helene; Quintero-Cortes, Leticia; Roussi, Georges
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4933 - 4938
13575-75-2
6,7-二甲氧基-3,4-二氢-2H-1-萘酮
→
反应条件
15288-02-5
+
15288-01-4
反应条件
hydrogen bromide
参考文献
Beugelmans, Rene; Chastanet, Jacqueline; Ginsburg, Helene; Quintero-Cortes, Leticia; Roussi, Georges
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4933 - 4938
13575-74-1
4-(3,4-二甲氧苯基)丁酸
→
反应条件
15288-01-4
反应条件
1: 93 percent / polyphosphoric acid / 4 h / 40 °C 2: 40 percent / HBr View Scheme
参考文献
Beugelmans, Rene; Chastanet, Jacqueline; Ginsburg, Helene; Quintero-Cortes, Leticia; Roussi, Georges
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4933 - 4938