O-(三甲基硅烷基)苯酚合成路线 （共 28 条）
反应条件
1: 80 percent / TFA / 0.1 h / 20 °C
2: 99 percent / NaOH / ethanol; H2O / 4 h / 20 °C
View Scheme
参考文献
Metallinos, Costa; Nerdinger, Sven; Snieckus, Victor
Organic Letters, 1999 , vol. 1, # 8 p. 1183 - 1186
反应条件
2: 70 percent / 30percent H2O2, n-Bu4NF, KHCO3 / methanol; tetrahydrofuran
View Scheme
参考文献
Tamao, Kohei; Yao, Hajime; Tsutsumi, Yasushi; Abe, Hideyuki; Hayashi, Takashi; Ito, Yoshihiko
Tetrahedron Letters, 1990 , vol. 31, # 20 p. 2925 - 2928
反应条件
1: tetrahydrofuran
3: 70 percent / 30percent H2O2, n-Bu4NF, KHCO3 / methanol; tetrahydrofuran
View Scheme
参考文献
Tamao, Kohei; Yao, Hajime; Tsutsumi, Yasushi; Abe, Hideyuki; Hayashi, Takashi; Ito, Yoshihiko
Tetrahedron Letters, 1990 , vol. 31, # 20 p. 2925 - 2928
反应条件
hydrogenchloride in methanol; water
Ambient temperaturedifferent pH values (0.1-10.0), solvents and times; Product distribution;
参考文献
Epp, James E. Van; Boyd, Derek R.; Berchtold, Glenn A.
Journal of Organic Chemistry, 1981 , vol. 46, # 9 p. 1817 - 1820
反应条件
1: pyridine / 3 h / Ambient temperature
2: 92 percent Chromat. / NaBr, NCS / acetic acid / 0.17 h / 60 °C
View Scheme
参考文献
Wilbur, D. S.; Stone, W. E.; Anderson, K. W.
Journal of Organic Chemistry, 1983 , vol. 48, # 9 p. 1542 - 1544
反应条件
1: triethylamine; 4-pyrrolidin-1-ylpyridine / tetrahydrofuran; hexane / 0.06 h / 55 °C / |Flow reactor
2: cesium fluoride / acetonitrile / 1 h / 80 °C
View Scheme
参考文献
Michel, Boris; Greaney, Michael F.
Organic Letters, 2014 , vol. 16, # 10 p. 2684 - 2687
反应条件
1: o-(trimethylsilyl)phenol With triethylamine; magnesium chloride in acetonitrile
T=20°C; 0.25 h;
2: formaldehyd in acetonitrile
T=20°C; 3 h;
参考文献
Yoshimura, Tomoyuki; Tomohara, Keisuke; Kawabata, Takeo
Journal of the American Chemical Society, 2013 , vol. 135, # 19 p. 7102 - 7105
反应条件
18-crown-6 ether; nonafluoro-n-butanesulfonyl fluoride; caesium carbonate in acetonitrile
T=60°C; 4 h; Inert atmosphere;
参考文献
Ikawa, Takashi; Nishiyama, Tsuyoshi; Nosaki, Toshifumi; Takagi, Akira; Akai, Shuji
Organic Letters, 2011 , vol. 13, # 7 p. 1730 - 1733
