反应条件
1: 1) lithium isopropylcyclohexylamide / 1) THF, -78 deg C to -50 deg C, 2) THF, DCM, -30 deg C, 16 h 2: 81 percent / LiBH4 / diethyl ether; tetrahydrofuran / 18 h / Ambient temperature 3: 3M HCl / methanol / 1 h / Heating 4: 80 percent / Ph3P, DEAD / tetrahydrofuran / 1.5 h / Ambient temperature View Scheme
参考文献
Versteeg, Marietjie; Bezuidenhoudt, Barend C. B.; Ferreira, Daneel
Tetrahedron, 1999 , vol. 55, # 11 p. 3365 - 3376
