n-butyllithium in diethyl ether 1.) -78 deg C, 30 min, 2.) -78 deg C, 1 h; -78 deg C to r.t. 30 min, then r.t., 1 h; Yields of byproduct given;

n-butyllithium in tetrahydrofuran; hexane 1.) -78 deg C, 10 min, 2.) -78 deg C, 2 h; Yield given;

potassium hydroxide in ethanol T=20°C; 1.5 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />48&nbsp;h;&nbsp;&nbsp;Ambient temperature;&nbsp;<br /> &nbsp;