2-氟-3-碘-5-甲基吡啶合成路线 （共 3 条）
反应条件
iodine; lithium diisopropyl amide in tetrahydrofuran 1.) -75 deg C, 4 h, 2.) -75 deg C, 2 h;
参考文献
Rocca, P.; Cochennec, C.; Marsais, F.; Thomas-dit-Dumont, L.; Mallet, M.; et al.
Journal of Organic Chemistry, 1993 , vol. 58, # 27 p. 7832 - 7838
反应条件
in tetrahydrofuran; hexane 2 h;
参考文献
EP1679003 A1, ;
Page/Page column 13-14 ;
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran T=-78°C; 2: With water in tetrahydrofuran T=-78 - 20°C;
参考文献
Wang, Le; Lin, Nan-Horng; Li, Qun; Henry, Rodger F.; Zhang, Haiying; Cohen, Jerome; Gu, Wen-Zhen; Marsh, Kennan C.; Bauch, Joy L.; Rosenberg, Saul H.; Sham, Hing L.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 18 p. 4603 - 4606
