2-[2-(2-氨基乙氧基)乙氧基]乙基氨基甲酸叔丁酯 N-Boc-3,6-二氧杂-1,8-辛二胺合成路线 （共 22 条）
反应条件
triethylamine in methanol T=35°C; 24 h;
参考文献
Bioconjugate Chemistry, , vol. 22, # 10 p. 2186 - 2197
反应条件
in dichloromethane T=0 - 20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 15 p. 4208 - 4212
反应条件
1: With triphenylphosphine in tetrahydrofuran 5 h; 2: With water in tetrahydrofuran 2 h;
参考文献
ChemBioChem, , vol. 11, # 12 p. 1769 - 1781
反应条件
hydrogen; palladium on activated carbon in methanol 16 h;
参考文献
WO2006/133144 A2, ;
Page/Page column 65; 70 ;
反应条件
hydrogenchloride in 1,4-dioxane T=0 - 20°C; 1.5 h;
参考文献
Journal of the American Chemical Society, , vol. 118, # 16 p. 3789 - 3800
反应条件
sodium hydroxide in dichloromethane
反应条件
ammonium hydroxide in methanol 24 h; Heating;
参考文献
Phytochemistry, , vol. 63, # 3 p. 315 - 334
参考文献
Tetrahedron Letters, , vol. 49, # 41 p. 6003 - 6006
反应条件
1: 54 percent / methanol / -78 - 20 °C 2: 97 percent / tetrahydrofuran / 3 h / 20 °C 3: 97 percent / aq. NH4OH / methanol / 24 h / Heating View Scheme
参考文献
Phytochemistry, , vol. 63, # 3 p. 315 - 334
