6,11-二氢二苯并[b,e]硫杂卓-11-酮合成路线 （共 23 条）
参考文献
Taljaard, Benjamin; Barton, Benita; McCleland, Cedric W.
South African Journal of Chemistry, 2004 , vol. 57, p. 44 - 48
反应条件
phosphoric acid; phosphorus pentoxide T=120 - 125°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 51, # 23 p. 4458 - 4460
反应条件
PPA T=195°C; 0.25 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 18 p. 2521 - 2526
反应条件
1: K2CO3 / dimethylformamide / 2 h / 100 °C 2: 33 percent / polyphosphoric acid / 3 h / 100 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 10 p. 2564 - 2573
反应条件
1: K2CO3 / dimethylformamide / 2 h / 100 °C 2: 33 percent / polyphosphoric acid / 3 h / 100 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 10 p. 2564 - 2573
反应条件
1: 65 percent 2: 67 percent / polyphosphoric acid / 115 °C View Scheme
参考文献
Synthetic Communications, , vol. 19, # 19 p. 3349 - 3352
反应条件
sodium amide 1) benzene, 50 deg C, 1 h, 2) reflux, 6 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 48, # 7 p. 1898 - 1909
反应条件
sodium amide 1) benzene, 2 h, 50 deg C, 2) ether, 5 h, reflux; Yield given. Multistep reaction;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 48, # 7 p. 1898 - 1909
反应条件
1: 1) Mg / 1) THF, 25 deg C, 20 min, 2) 60 deg C, 2,5 h 2: 91 percent / SOCl2 / CHCl3 / 0.5 h / 0 °C 3: 44 percent / hexamethylphosphoamide / 1 h / 70 °C 4: NiCl2, NaBH4 / ethanol; dioxane; propan-2-ol / 5 h / 25 °C 5: hydrogen chloride, ethanol 6: 46 percent / sodium formate, formic acid / H2O / 4 h / 95 °C View Scheme
参考文献
Ohishi; Hayashida; Mukai; Kimura; Nagahara
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 4 p. 1066 - 1068
反应条件
hydrogenchloride 1.) THF, toluene, 65 deg C, 2 h, 2.) 1 h, 3.) 75 deg C, 1.5 h, ethanol; Multistep reaction;
参考文献
Jalander, Lars; Oksanen, Lasse; Taehtinen, Johanna
Synthetic Communications, 1989 , vol. 19, # 19 p. 3349 - 3352
