1: 94 percent / Pd2(dba)3*CHCl3, (S)-BINAP, 1,2,2,6,6-pentamethylpiperidine / N,N-dimethyl-acetamide / 1.5 h / 100 °C 2: 80 percent / 3M aq. HCl / tetrahydrofuran / Ambient temperature 3: 1.) Et3N, MgSO4, 2.) LiAlH4 / 1.) THF, RT, overnight, 2.) THF, reflux, 1.5 h 4: BBr3 / CH2Cl2 / 23 °C 5: NaH / diethyl ether View Scheme