1: With palladium diacetate; tetra-n-butylammonium acetate; potassium carbonate; potassium chloride in N,N-dimethyl-formamide T=90°C; Heck reaction; 6 h; 2: With hydrogenchloride; water in N,N-dimethyl-formamide
1: With lithium amide; [(CyPF-tBu)PdCl2] in ethylene glycol dimethyl ether T=80°C; 20 h; Sealed vial; 2: With hydrogenchloride in ethylene glycol dimethyl ether; water T=20°C; 0.0833333 h; 3: With sodium hydrogencarbonate in ethylene glycol dimethyl ether; water Product distribution / selectivity;
参考文献
YALE UNIVERSITY
Patent: WO2007/109365 A2, 2007 ;
Location in patent: Page/Page column 48-49; 52 ;
