2-[4-[(2-乙基-5,7-二甲基咪唑并[5,4-b]吡啶-3-基)甲基]-2,6-二丙基苯氧基]-2-苯基乙酸合成路线 （共 14 条）
反应条件
1: K2CO3 / acetone / Heating 2: 1 N aq. NaOH / methanol View Scheme
参考文献
Dhanoa; Bagley; Chang; Lotti; Chen; Kivlighn; Zingaro; Siegl; Chakravarty; Patchett; Greenlee
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3738 - 3742
反应条件
1: 93 percent / n-Bu4NF / tetrahydrofuran 2: K2CO3 / acetone / Heating 3: 1 N aq. NaOH / methanol View Scheme
参考文献
Dhanoa; Bagley; Chang; Lotti; Chen; Kivlighn; Zingaro; Siegl; Chakravarty; Patchett; Greenlee
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3738 - 3742
反应条件
1: NBS, AIBN / CCl4 / Heating 2: Cs2CO3 / dimethylformamide 3: Ph3P, CBr4 / CH2Cl2 4: Cs2CO3 / dimethylformamide 5: 1 N aq. NaOH / methanol View Scheme
参考文献
Dhanoa; Bagley; Chang; Lotti; Chen; Kivlighn; Zingaro; Siegl; Chakravarty; Patchett; Greenlee
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3738 - 3742
反应条件
1: Ph3P, CBr4 / CH2Cl2 / 0 - 20 °C 2: Cs2CO3 / dimethylformamide 3: Ph3P, CBr4 / CH2Cl2 4: Cs2CO3 / dimethylformamide 5: 1 N aq. NaOH / methanol View Scheme
参考文献
Dhanoa; Bagley; Chang; Lotti; Chen; Kivlighn; Zingaro; Siegl; Chakravarty; Patchett; Greenlee
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3738 - 3742
