(2R,3S)-3-(苯甲酰基氨基)-2-羟基苯丙酸乙酯合成路线 （共 43 条）
反应条件
1: ethyl (2R,3S)-3-{[(R)-1-phenylethyl]amino}-2-hydroxy-3-phenylpropanoate With hydrogenchloride; hydrogen; palladium dihydroxide in ethanol T=20°C; P=760 Torr; 15 h; 2: benzoyl chloride With sodium hydrogencarbonate in ethyl acetate T=0°C; 0.25 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 16-17 p. 2421 - 2430
反应条件
Chromium (III) chloride; [Ru(DMF)nCl2]2; hydrogen; (2S, 4S)-(-)-2,4-bis(diphenylphosphino)pentane in ethanol; dichloromethane T=60°C; P=22801.5 Torr; 48 h; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 22, # 24 p. 2110 - 2116
反应条件
hydrogen; palladium on activated charcoal in ethanol Hydrogenation; P=2585.74 Torr; 6 h;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 38, # 3 p. 283 - 286
反应条件
potassium phosphate buffer; D-glucose T=28°C; 48 h; Hansenula polymorpha SC 13865; cells of various microorganisms, var. reaction time; Product distribution;
参考文献
Journal of the American Oil Chemists' Society, , vol. 72, # 11 p. 1247 - 1264
反应条件
hydrogenchloride T=20°C; 1.5 h;
参考文献
Tetrahedron Asymmetry, , vol. 16, # 18 p. 3099 - 3106
反应条件
sodium hydrogencarbonate in ethyl acetate T=0°C; 0.25 h;
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 20 p. 3096 - 3099
反应条件
1: HCl; H2 / Pd(OH)2 on C / ethanol / 15 h / 20 °C / 760 Torr 2: 10.5 mg / NaHCO3 / ethyl acetate / 0.25 h / 0 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 20 p. 3096 - 3099
反应条件
1: molecular sieves 4 Angstroem / Rh2(OAc)4 / CH2Cl2 / 10 h / 0 °C 2: 49.0 mg / para-toluenesulfonic acid / methanol; H2O / 1 h / 20 °C 3: HCl; H2 / Pd(OH)2 on C / ethanol / 15 h / 20 °C / 760 Torr 4: 10.5 mg / NaHCO3 / ethyl acetate / 0.25 h / 0 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 20 p. 3096 - 3099
反应条件
Lindnera fabiani CBS 5640 yeast cells T=30°C; pH=7; 72 h; Microbiological reactionaq. phosphate buffer; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 22, # 24 p. 2110 - 2116
反应条件
1: Escherichia coli expressing dehydrogenase YGL039w; glucose; KPi / XAD-4 resin; air / H2O / 24 h / 30 °C / pH 5.6 2: 99 percent / K2CO3 / dimethylformamide; H2O / 5 h / 20 °C 3: 55 percent / BF3*OEt2 / 3 h 4: 85 percent / aq. HCl / ethanol / 6 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 23 p. 9654 - 9657
